Today was officially my last day of semester, marked by the last of my exams.
Semester 5 was one of the hardest yet, for several reasons. Chiefly, the courses seemed boring. Macromolecular & Cellular Biochemistry was very difficult to deciper, and the majority of it was experiment specific. Even so, it was great to learn about intracellular signalling and the control mechanisms involved with how certain genes are ’switched on’ or ’switched off’. We hear these terms in our first couple of years, but we don’t know what it really meant until this semester. Finally, it seems, the gaps are being filled in. There’s satisfaction in this, but little else. I’ll never understand how the lecturer (who was foreign) managed to add another syllable to the term ‘endoplasmic reticulum.’
The lecturers were also, for the most part, un-engaging. It took me a while to realise that I did find immunology interesting, I was just reflecting the lecturers’ attitudes to the course, for the majority of them weren’t all that interested. If ever you want to be amazed by the human body – study immunology in depth. I was amazed by the delicate and comprehensive control of immune cells in the body, many of which have the capacity to be extremely destructive. Study autoimmune disease for examples. Also, the human genome is comprised of a mere 30,000 genes, and yet the immune system can produced thousands and thousands of antibodies – each different from the last. How? Look it up. Oh, and if you’re stuck for an answer in an exam, do what Dr Cameron (from House) does – make Systemic Lupus Erythematosis your answer.
Molecular Diagnostics was great fun speaking from a practical sense. There has been no other course with such a diverse lab schedule, where one week you may be performing blood smears on your lab partner, the next week you’re performing direct ELISA to diagnose Dengue Fever, and the week after that you’re performing paternity tests using forensic techniques. The content of the course was a regression to first year simplicity because of the volume of information, which was unfortunate. But learning that blood groups extend from A, B, O and AB to another 60 types was priceless, as was hearing about the forensic inquest into the Brisbane Prostitute Murders – a lecture presented by the actual forensic scientist who helped solve the case. The story was gory, but by god we were all enthralled.
Molecular Biology was certainly a chore, but only because of the monotonous men who presented it. Frustrating times included having to learn about Drosophila (fruit fly) development- because of course they’re going to be our patients in the future. As equally frustrating was being presented with a difficult concept, and told ‘we’re not sure exactly how this works, or is activated, so just understand what you can.’ How can I understand this when you can’t? But in spite of this, genetics is always interesting. I was amazed to find that a fly can develop all of its different body segments from a simple protein gradient inside the cell. And I’ll not forget my exam answer to the homeotic genes: bithorax, ultrabithorax, antennapedia, proboscopedia…and wikipedia.
So that sums-up the fifth of six semesters in Biomedical Science. I leave in a few weeks to go back to Heron Island for shark research, and when I get back, the final stretch begins. And you know what? I think i’m over feeling burned-out.